Alpha Card was established in 1998 and is owned by American Express. The organization issues cards (via Alpha Card CVBA/SCRL) and acquires merchants (via Alpha Card Merchant Services CVBA/SCRL) on the American Express Network in Belgium and Luxembourg.

As from October 2011, all operational services for the American Express brand have been integrated in the Alpha Card organisation.
The company consists of 180 employees focused on sales, marketing and after sales service.